Description
Chemical Identity
Adamax (Semax Derivative) analytical reference compound. Molecular weight ~864 Da.
Research Overview
Adamax is a modified analog of Semax, a synthetic heptapeptide derived from the ACTH(4-7) fragment (Met-Glu-His-Phe) with a C-terminal Pro-Gly-Pro extension for metabolic stability. The Adamax modification incorporates structural changes designed to enhance receptor binding affinity and resistance to enzymatic degradation compared to the parent Semax compound. Like Semax, Adamax targets neurotrophic factor modulation pathways.
Adamax research builds on the extensive body of work surrounding Semax, which has been approved in Russia since 1996 for treatment of stroke and cognitive disorders. Semax and its analogs are studied for their ability to upregulate brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) expression. The ACTH(4-7) core sequence interacts with melanocortin receptors (MC3R, MC4R) and has been shown to influence hippocampal plasticity, neuronal survival, and immune modulation in preclinical models. Adamax represents a structural optimization approach to improving the pharmacological profile of this peptide class.
Specifications
| Molecular Weight | ~864 Da |
| Molecular Formula | C38H52N10O11S |
| Purity | >=98% (HPLC) |
| Appearance | White to off-white lyophilized powder |
| Format | Lyophilized powder, sterile filtered |
| Solubility | Soluble in bacteriostatic water, sterile water, or normal saline |
| Storage | Store at -20°C (lyophilized). Reconstituted: 2-8°C, use within 30 days |
| Shipping | Ambient temperature (stable in lyophilized form) |
Each lot is accompanied by a Certificate of Analysis (COA) documenting purity, identity, and endotoxin testing results.
Research Applications
Adamax (Semax Derivative) has been documented in the published scientific literature across the following research areas:
- Neuropeptide analog structure-activity research
- BDNF and NGF pathway modulation studies
- Modified peptide stability and bioavailability research
- Melanocortin receptor interaction studies
- Cognitive function and neuroplasticity research models
Researchers should consult the primary literature for experimental protocols, concentrations, and conditions relevant to their specific area of investigation involving Adamax (Semax Derivative).
Storage and Handling
Adamax (Semax Derivative) is supplied as a lyophilized powder and should be stored at -20°C upon receipt for long-term stability. Protect from light, moisture, and repeated temperature fluctuations. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.
For reconstitution, add sterile water or an appropriate buffer slowly along the vial wall. Gently swirl to dissolve. Reconstituted Adamax (Semax Derivative) solutions should be stored at 2-8°C and used within 30 days. Aliquoting is recommended. Consult the Safety Data Sheet (SDS) for detailed handling guidance.
For laboratory research use only (in vitro). Not for human or animal use. Not for diagnostic, therapeutic, or clinical purposes. Adamax (Semax Derivative) is supplied as an analytical reference compound for use by qualified research personnel at accredited institutions. Prescott Bio Canada does not provide guidance on administration, dosing, or use in living organisms.