- Dispatched from BC same/next business day
- HPLC purity ≥98% per lot
- 50mg per vial, 10 vials/kit
- Batch-specific HPLC + MS CoA
Landing page
5-Amino-1MQ in Canada — research-grade vials, lot-tested
Shipped Across Canada in 2-4 business days
Small-molecule NNMT inhibitor (not a peptide) supplied as lyophilized 50 mg vials for pre-clinical NAD+-salvage and adipocyte-metabolism research. 10 vials per kit. HPLC + MS release testing per lot.
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Vial size
Ships today if ordered before 14:00 PT. CoA PDF emailed within 24h of ship confirmation. CAD invoicing available.
What is 5-Amino-1MQ, and how does it differ from a peptide?
5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), studied in the pre-clinical adipocyte and NAD+ salvage-pathway literature. Prescott Bio supplies it as a lyophilized 50mg vial (10 vials per kit). Every lot is independently assayed by HPLC (purity) and mass spectrometry (identity).
Read more about the mechanism
NNMT methylates nicotinamide and thereby diverts substrate away from the NAD+ salvage pathway. In the pre-clinical adipocyte and cellular-metabolism literature, NNMT inhibitors are studied for their effect on the intracellular NAD+ pool and on adipose-tissue methyl-group balance.
5-Amino-1MQ is a small molecule rather than a peptide, so its handling and reconstitution profile differ from the peptide catalog. Certificates of analysis are batch-specific and available on request via the /coa lookup. All product is sold strictly for laboratory research use only.
Assay and lot testing
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HPLC purity
Reverse-phase HPLC assay on every synthesized lot.
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Mass spec identity
MS identity confirmation against the theoretical mass.
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Batch-specific CoA
Lot certificates available via /coa.
Why buy domestic, and how fast does it arrive?
- Domestic dispatch. Ships from our British Columbia facility. No cross-border customs risk on Canadian orders.
- 2-4 day delivery. Canadian orders arrive 2-4 business days after dispatch, with tracking.
- CAD pricing. Prices quoted in Canadian dollars. No FX conversion, no duty at delivery.
How does 5-Amino-1MQ compare with NAD+ or Retatrutide?
All ship from Canada, lot-tested. Click any column to see the PDP.
5-Amino-1MQ
NNMT small-molecule inhibitor
Blocks nicotinamide methylation to preserve substrate for the NAD+ salvage pathway.
From $85 / vial
NAD+
Redox coenzyme
Direct NAD+ presentation — central to sirtuin and cellular-metabolism research.
From $70 / vial
Retatrutide
GLP-1 / GIP / glucagon triple agonist
Long-acting incretin analog studied in metabolic-axis dose-response designs.
From $70 / vial
Why buy domestic vs cross-border import?
| Prescott Bio (Canadian domestic) | Cross-border import | |
|---|---|---|
| Ship time to Canadian lab | 2-4 business days from BC | 7-21 days plus CBSA hold risk |
| Currency and invoicing | CAD, GST/HST line-item | USD, FX friction, no CAD invoice |
| Customs and duty | None — dispatched inside Canada | CBSA declaration; duty and delay risk |
| CoA delivery | Batch-specific HPLC + MS per lot, PDF on request | Varies — often composite or template |
| Cold-chain risk | Domestic transit within stability window | Multi-week transit may exceed thermal wrap |
Questions Canadian labs ask before their first order
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What is 5-Amino-1MQ?
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT). NNMT methylates nicotinamide and thereby diverts substrate away from the NAD+ salvage pathway; blocking NNMT is studied for its effect on intracellular NAD+ levels and on adipose-tissue methyl-group balance in pre-clinical models. -
How does it relate to NAD+ research?
5-Amino-1MQ acts upstream of NAD+ by inhibiting NNMT rather than supplementing the coenzyme directly. The pre-clinical rationale is that reducing nicotinamide methylation preserves substrate for the NAD+ salvage pathway. Researchers who study NAD+ dynamics sometimes pair the two approaches in the same study design; others compare them head-to-head. -
How is 5-Amino-1MQ reconstituted?
- Wipe the vial stopper with an alcohol swab.
- Draw the target volume of diluent appropriate for the small-molecule stock (typically 1-2 mL).
- Inject the diluent slowly against the vial wall.
- Swirl gently to dissolve. Do NOT shake.
- Store the reconstituted vial at 2-8°C. Use within 30 days.
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How is it stored?
- Refrigerate lyophilized vials at 2-8°C until first use.
- After reconstitution with bacteriostatic water, store at 2-8°C and use within 30 days.
- For storage beyond six months, freeze the sealed lyophilized vial at -20°C.
- Avoid repeated freeze-thaw cycles.
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How fast does Prescott Bio ship?
Orders placed before 14:00 PT ship the same business day from our British Columbia facility. Canadian orders arrive 2-4 business days after dispatch. -
Is the CoA a small-molecule HPLC + MS or a peptide-style assay? 5-Amino-1MQ isn't a peptide.
Correct — 5-Amino-1MQ is a small molecule, not a peptide. The CoA runs small-molecule HPLC and MS confirmation against the expected structure. No peptide-specific sequencing applies.