Product overview
PT-141 10mg/10vials is a sterile lyophilized research peptide. PT-141 (bremelanotide) is a synthetic cyclic heptapeptide and an active metabolite of Melanotan-2 from which the C-terminal amide has been removed. It is studied as a non-selective melanocortin-receptor agonist with notable activity at the central MC4R receptor, and has a substantial preclinical literature on MC4R-mediated CNS endpoints.
Independently assayed by HPLC and MS, and lot-traceable to the source preparation.
Typical research dose range
Published preclinical CNS-pharmacology protocols use PT-141 in animal models in the range of roughly 0.5-2 mg per administration, with timing keyed to the specific endpoint under investigation. Researchers should consult source literature for the specific endpoint and model organism.
Stack and pairing
PT-141 is studied alongside Melanotan-2 in comparative melanocortin-receptor pharmacology work, where the two molecules provide a contrast between pigmentation-leaning (MT-2) and CNS-leaning (PT-141) downstream profiles despite their shared receptor family.
Reconstitution and storage
Reconstitute each vial with 1-2 mL of bacteriostatic water for the target working concentration. Use sterile technique. Once reconstituted, store at 2-8 °C and use within 30 days for best stability.
Lyophilized vials should be kept refrigerated at 2-8 °C until first use. For long-term storage beyond six months, store at -20 °C in the original sealed vial. Avoid repeated freeze-thaw cycles.
Kit contents
- 10 × 10mg vials of lyophilized PT-141
- 1 × certificate of analysis (lot-specific)
- 1 × handling and reconstitution insert
